2020~
91. Synthesis of Multi-substituted Pyranoindol-1-ones Using Iridium-Catalyzed Intramolecular C-H Amination of 3-Amino-4-phenyl-2-pyrones
R. Yamasaki, K. Ueda, K. Fukuoka, I. Hachiya*
Asian Journal of Organic Chemistry 2025, 14, e70173. DOI: doi.org/10.1002/ajoc.70173.
90. Synthesis of 1-Naphthylamines Utilizing [4+2] Cycloaddition between 3-Amino-2pyrones and Benzynes
Kawazoe, M. Shiraishi, I. Hachiya*
Asian Journal of Organic Chemistry 2025, 14, e00533. DOI: doi.org/10.1002/ajoc.202500533.
89. Synthesis of Multi-Substituted β-Carbolin-1-ones via Iridium-Catalyzed Intramolecular C-H/N-H Amination of 3-Amino-2-pyridones
H. Mori, M. Morimura, A. Okada, H. Masuda, I. Hachiya*
Asian Journal of Organic Chemistry 2025, 14, e00425. DOI: doi.org/10.1002/ajoc.202500425
88. Synthesis and Structural Properties of para-Diselenopyrazines,
C. Hüßler, M. C. Dietl, J. Kahle, E. F. Lopes, M. Kawamura, P. Krämer, F. Rominger, M. Rudolph, I. Hachiya, S. K. Hashmi*
Chemical. Communications 2024, 60, 3786-3789. DOI: 10.1039/d4cc00460d.
87. Synthesis of 2,3,6-Trisubstituted β-Carbolin-1-ones Utilizing 3-Amino-2-pyridone Synthesis
H. Masuda, H. Morishita, R. Sasaki, K. Takahata, K. Uemura, I. Hachiya*
ChemistrySelect 2022, 7 (21), e202201737. DOI: 10.1002/slct.202201737
86. Synthesis of 3,6-Disubstituted 4-Ethoxycarbonylpyranoindol-1ones Utilizing 3Amino-2-pyrone Synthesis
K. Fukuoka, K. Imai, K. Hirano, S. Goto, R. Miura, I. Hachiya*
Asian Journal of Organic Chemistry 2022, 11 (6), e202200110. DOI: 10.1002/ajoc.202200110
85. Domino 1,4- and 1,4-Addition Reactions of Ketene Silyl Thioacetals to Dialkynyl Imines Promoted by Scandium Triflate: Synthesis of Multifunctionalized δ-Lactams
Y. Watanabe, K. Isaka, K. Sato, S. Kokado, A. Mizutani, I. Hachiya*
Asian Journal of Organic Chemistry 2022, 11 (1), e202100672. DOI: 10.1002/ajoc.202100672
84. Umpolung Reaction of α-Tosyloximino Ester Using a Flow System
K. Ota, S. Fukumoto, T. Iwase, I. Mizota, M. Shimizu,* I. Hachiya*
Synlett 2020, 31 (19), 1930−1936. DOI: 10.1055/s-0040-1707265
83. Synthesis of 2,3-Disubstituted 4‑Ethoxycarbonyl-β-carbolin-1-ones: Application to the Synthesis of SL651498 and Its Analogue
R. Miura, S. Goto, T. Hashimoto, I. Hachiya*
ACS Omega 2020, 5 (25), 15631−15656. DOI: 10.1021/acsomega.9b01199
2010~
82. Domino 1,4- and 1,6-Addition Reactions of Ketene Silyl Acetals to Dialkynyl Imines Promoted by Aluminum Chloride: Synthesis of Multifunctionalized β‑Lactams
I. Hachiya,* K. Nakamura, M. Hara, K. Sato, M. Shimizu*
The Journal of Organic Chemistry 2019, 84 (22), 14770−14794. DOI: 10.1021/acs.joc.9b02364
81. Titanium Tetraiodide/Trimethylsilyl Iodide Synergistically Induced Cyclization of N‑(2-Cyanophenyl)-benzamides into 2‑Aryl-4-Iodoquinazolines
I. Hachiya,* S. Nagoshi , M. Shimizu*
ACS Omega 2019, 4 (6), 10463−10473.DOI: 10.1021/acsomega.9b01199
80. Synthesis of α-Carbolines Using Palladium-Catalyzed Intramolecular Amination of 3-(2-Chlorophenyl)-2-Aminopyridines
I. Hachiya,* S. Shimada, M. Fukutomi, R. Miura, M. Shimizu*
ChemistrySelect 2019, 4 (2), 469−472.DOI: 10.1002/slct.201803948
79. Synthesis of 2-Aminopyridinium Salts from 2-Iminopyridines as a Starting Material
I. Hachiya, M. Fukutomi , N. Kugisaki, S. Shimada, M. Shimizu*
Heterocycles 2017, 94 (12), 2215-2221. DOI: 10.3987/COM-17-13816
78. Titanium Tetraiodide Induced Cyclization of Cyanoketones into 3-Aryl-1-iodoisoquinolines
K. Yashiro, K. Sakata, I. Hachiya M. Shimizu*
Heterocycles 2016, 92 (11), 2032-2046. DOI: 10.3987/COM-16-13560
77. Titanium Tetraiodide-mediated Diastereoselective Iodo-aldol and Mannich Reactions of γ-Alkoxy-α,β-alkynyl Ketone Derivatives
K. Yashiro, S. Ito, S. Kayaki, K. Sakata, I. Mizota, I. Hachiya, M. Shimizu*
Tetrahedron 2016, 72 (43), 6875-6885. DOI: 10.1016/j.tet.2016.09.020
76. of (±)-Muscopyridine Analogue Using Ring-Expansion Reaction of Cyclic β-Keto Ester via Conjugate Addition to Alkynyl Imine
I. Hachiya, N. Kugisaki, R. Agata, H. Matsumoto, Y. Yamada, M. Shimizu*
Tetrahedron 2015, 71 (35), 5824-5829. DOI: 10.1016/j.tet.2015.05.090
75. 2-Aryl-4-quinolone Synthesis Using the Thermal Rearrangement of Iminocyclobutenones
I. Hachiya, K. Yokoyama, A. Ito, M. Shimizu*
Heterocycles 2015, 90 (1), 97-103. DOI: 10.3987/COM-14-S(K)13
74. Chiral β-Lactam Synthesis through the Enantioselective Reduction of Iminocyclobutenones and the Thermal Rearrangement of Aminocyclobutenones
I. Hachiya, A. Ito, M. Shimizu*
Asian Journal of Organic Chemistry 2014, 3 (5), 614‑618. DOI: 10.1002/ajoc.201402005
73. Two-Step Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from 2,3-Butanedione
I. Hachiya, T. Yamamoto, T. Inagaki, T. Matsumoto, A. Takahashi, I. Mizota, M. Shimizu*
Heterocycles 2014, 88 (1), 607-612. DOI: 10.3987/COM-13-S(S)8
72. Regioselective Ring-Opening Reaction of 2-Mono-Substituted Azetidin-3-ones Promoted by the Combined Use of Titanium Tetraiodide and Its Chloro or Bromo Counterpart
I. Hachiya, S. Ito, S. Kayaki, M. Shimizu*
Asian Journal of Organic Chemistry 2013, 2 (11), 931-934. DOI: 10.1002/ajoc.201300165
71. Synthesis of α-Amino Ketones and O-Alkyloximes by Titanium Tetrahalide Promoted Ring-Opening Reaction of 2-Mono-substituted Azetidin-3-ones and Their O-Alkyloximes
S. Ariga, S. Hata, D. Fukuda, T. Nishi, I. Hachiya, M. Shimizu*
Heterocycles 2012, 86 (2), 1187-1210.DOI: 10.3987/COM-12-S(N)74
70. Regioselective Ring-Opening Reaction of 2-Mono-Substituted Azetidin-3-ones Promoted by the Combined Use of Titanium Tetraiodide and Its Chloro or Bromo Counterpart
S. Hata, D. Fukuda, I. Hachiya, M. Shimizu*
Heterocycles 2012, 84 (1), 301-307. DOI: 10.3987/COM-11-S(P)26
69. Reductive Aminopropylation of Ketene Silyl (Thio)acetals Leading to the Synthesis of δ-Amino Esters
I. Mizota, S. Agatani, I. Hachiya, M. Shimizu*
Tetrahedron Letters 2011, 52 (41), 5388-5391. DOI: 10.1016/j.tetlet.2011.08.054
68. Double Nucleophilic Addition to Acrolein with Ketene Silyl Acetals and Allylborolanes Catalyzed by Proline
M. Shimizu,* M. Kawanishi, A. Itoh, I. Mizota, I. Hachiya
Chemistry Letters 2011, 40 (8), 862-863. DOI: 10.1246/cl.2011.862
67. Titanium Tetraiodide-Promoted Reductive Enolate Formation of α-Tosyloxy Ketone Derivatives and Aldol Reaction with Aldehydes
I. Hachiya, T. Inagaki, Y. Ishihara, M. Shimizu*
Bulletin of the Chemical Society of Japan 2011, 84 (4), 419-421.DOI: 10.1246/bcsj.20100363
66. Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from (Z)-But-2-ene-1,4-diol or But-3-yne-1,4-diol
I. Hachiya, T. Matsumoto, T. Inagaki, A. Takahashi, M. Shimizu*
Heterocycles 2010, 82 (1), 449-460. DOI: 10.3987/COM-10-S(E)16
65. Titanium Tetraiodide-Promoted Tandem Prins Reaction of Alkynes with Acetals: Synthesis of (Z,Z)-1,5-Diiodo-1,3,5-triarylpenta-1,4-dienes
M. Shimizu,* K. Okura, T. Arai, I. Hachiya
Chemistry Letters 2010, 39 (10), 1052-1054. DOI: 10.1246/cl.2010.1052
64. Use of N-Allylidene-1,1-diphenylethanamine as a Latent Acrolein Synthon in the Double Nucleophilic Addition Reaction of Ketene Silyl (Thio)acetals and Allylborolanes
M. Shimizu,* M. Kawanishi, I. Mizota, I. Hachiya
Organic Letters 2010, 12 (16), 3571-3573. DOI: 10.1021/ol101061t
63. A New Method for the Synthesis of Multisubstituted Pyrroles of Biological Interest by Double Nucleophilic Addition to α,β-Unsaturated Imines
A. Takahashi, S. Kawai I. Hachiya, M. Shimizu*
European Journal of Organic Chemistry 2010, (1), 191-200. DOI: 10.1002/ejoc.200901055
62. Facile Synthesis and Ring-Opening of 4-(Tributylstannyl)pyrrolidine-2-carboxylates
M. Shimizu,* H. Ando, H. Shibuya, I. Hachiya
Heterocycles 2010, 80 (2), 773-778. DOI: 10.3987/COM-09-S(S)73
61. Reductive Aldol and Mannich-Type Reactions of Azetidin-3-ones Promoted by Titanium Tetraiodide
S. Hata, D. Fukuda, I. Hachiya, M. Shimizu*
Chemistry-An Asian Journal 2010, 5 (3), 473-477. DOI: 10.1002/asia.200900457
2000~
60. N-Allylideneamines Derived from Acrolein: Synthesis and Use as Acceptors of Two Nucleophiles
I. Mizota, Y. Matsuda, I. Hachiya, M. Shimizu*
European Journal of Organic Chemistry 2009, (24), 4073-4084. DOI:
59. Stereodivergent Synthesis of β-Lactams Using Thermal Rearrangement of Aminocyclobutenones
I. Hachiya, T. Yoshitomi, Y. Yamaguchi, M. Shimizu*
Organic Letters 2009, 11, (15), 3266-3268. DOI:
58. Titanium Tetraiodide Induced Cyclization of 2-(2-Cyanoalk-1-enyl)-β-keto Esters into 2-Iodopyridines
I. Hachiya, Y. Minami, M. Shimizu*
Heterocycles 2009, 79 (1), 365-371. DOI:
57. Regioselective Double Nucleophilic Addition Reaction Leading to the Synthesis of β-Lactams
A. Takahashi, S. Kawai, I. Hachiya, M. Shimizu*
Heterocycles 2008, 76 (1), 203-208. DOI:
56. Synthesis of N-Allylideneamines and Their Use for the Double Nucleophilic Addition of Ketene Silyl (Thio)acetals and Trimethylsilyl Cyanide
I. Mizota, Y. Matsuda, I. Hachiya, M. Shimizu*
Organic Letters 2008, 10 (18), 3977-3980. DOI:
55. Synthesis of Multi-Substituted 2-Iminopyridine Using Conjugate Addition of Ethyl Cyanoacetate Derivatives to Alkynyl Imines
I. Hachiya, Y. Minami, T. Aramaki, M. Shimizu*
European Journal of Organic Chemistry 2008, (8), 1411-1417. DOI:
54. 3-Iodo-3-trimethylsilylpropenal as a Useful Unit for Pinacol Coupling and Subsequent Functional Group Transformations
M. Shimizu,* H. Okimura, N. Manabe, I. Hachiya
Chemistry Letters 2008, 37 (1), 28-29. DOI:
53. Titanium Tetraiodide Promoted Reductive Opening of 2-(1-Benzyloxyiminoethyl)aziridines, Leading to Aza-Aldol Reaction
M. Shimizu,* S. Nishiura, I. Hachiya
Heterocycles 2007, 74 (1), 177-183. DOI:
52. Diastereoselective Approach to an HIV Protease Inhibitor Intermediate Using a Cation-Exchange Resin Mediated Mannich-Type Reaction
M. Shimizu,* Y. Hayashi, R. Hamanaka, I. Hachiya
Heterocycles 2007, 74 (1), 177-183. DOI:
51. Stereodivergent Synthesis of Both (2S)- and (2R)-1-Monoricinolein Derivatives by Lipase-Catalyzed Hydrolysis or Transesterification Directed to New Ferroelectric Liquid Crystals
I. Hachiya, Y. Sugiura, H. Araki, O. Inaoka, M. Shimizu,* M. Akita, T. Hamaguchi
Tetrahedron: Asymmetry 2007, 18 (8), 915-918. DOI:
50. Diastereoselective Reduction of α-Imino Esters with Tris(trimethylsilyl)aluminum
M. Shimizu,* Y. Niwa, T. Nagai, I. Hachiya
Heterocycles 2007, 72 (1),, 127-132. DOI:
49. Aza-Prins Reaction Promoted by Titanium Tetraiodide and Iodine
M. Shimizu,* T. Baba, S. Toudou, I. Hachiya
Chemistry Letters 2007, 36 (1), 12-13. DOI:
48. Ring Expansion Reaction of Cyclic β-Keto Esters or α-Cyano Ketones via Conjugate Addition to Alkynyl Imines: The Synthesis of Functionalized Medium-Sized Carbocycles
I. Hachiya, W. Maehara, Y. Yamada, T. Kamiki, M. Shimizu*
Synlett 2006, 17 (19), 3271-3274. DOI:
47. Titanium Tetraiodide Mediated Reductive Opening of Aziridines, Leading to the Aldol and Mannich-Type Reactions
M. Shimizu,* H. Kurokawa, S. Nishiura, I. Hachiya
Heterocycles 2006, 70 (1), 57-64. DOI:
46. 3,4,5,6-Tetrasubstituted-2-pyridone Synthesis via Nucleophilic Addition of Active Methine Compounds to Dialkynyl Imines Directed to the Synthesis of (-)-A58365A
I. Hachiya, S. Fukushima, M. Shimizu*
Heterocycles 2006, 69 (1), 43-48. DOI:
45. Remarkable Effects of Additives to Facilitate Aza-Mannich Type Reaction: A Rapid Access to β-Amino Ketone O-Alkyl Oximes
M. Shimizu,* M. Tanaka, T. Itoh, I. Hachiya
Synlett 2006, 17 (11), 1687-1690. DOI:
44. Synthesis of Bicyclic Compounds Containing a 2-Pyridone Structure by Addition of Malonic Esters to Alkynylpyridines, Pyrimidine, and Thiazoles
I. Hachiya, M. Atarashi, M. Shimizu*
Heterocycles 2006, 67 (2), 523-528. DOI:
43. A Cation-Exchange Resin Promoted Imino Aldol Reaction of Chiral Alkoxy Ketene Silyl Acetals with α,β-Unsaturated Imines, Leading to a Facile Synthesis of β-Lactams
M. Shimizu,* M. Tachi, S. Fukushima, I. Hachiya
Heterocycles 2005, 66 (1), 75-80. DOI:
42. Double Nucleophilic Addition of Trimethylsilyl Cyanide to α,β-Unsaturated Aldimines Promoted by Aluminum Chloride: Preparation of 2-Aminopentanedinitrile
M. Shimizu,* M. Kamiya, I. Hachiya
Chemistry Letters 2005, 34 (10), 1456-1457. DOI:
41. A Cation-Exchange Resin Promoted Imino Aldol Reaction, Leading to the Synthesis of 2-Isocephem and 2-Oxa-isocephem
M. Shimizu,* M. Tachi, I. Hachiya
Chemistry Letters 2004, 33 (10),, 1394-1395. DOI:
40. Stereodivergent Synthesis of (2R)-2,3-Diricinolein by Lipase-Catalyzed Hydrolysis of Triricinolein
I. Hachiya, A. Makino, M. Shimizu,* M. Akita, T. Hamaguchi
Tetrahedron: Asymmetry 2004, 15 (16), 2451-2454. DOI:
39. 3,4,6-Trisubstituted-2-pyrone Synthesis via the Nucleophilic Addition of 2-Alkyl Meldrum’s Acid to Alkynyl Ketone
I. Hachiya, H. Shibuya, K. Hanai, M. Shimizu*
Letters in Organic Chemistry 2004, 1 (4), 233- 236. DOI:
38. Synthesis of 5-Acetyl-2-pyridones via Nucleophilic Addition of β-Ketoesters to Alkynyl Imines
I. Hachiya, K. Ogura, M. Shimizu*
Synthesis 2004, 36 (9), 1349-1352. DOI:
37. Double Nucleophilic Addition of Ketene Silyl (Thio)acetals and Trimethylsilyl Cyanide to α,β-Unsaturated Aldimines Promoted by Aluminum Chloride
M. Shimizu,* M. Kamiya, I. Hachiya
Chemistry Letters 2003, 32 (7), 606-607. DOI:
36. Novel 2-Pyrone Synthesis via the Nucleophilic Addition of Active Methine Compounds to 2-Alkynone
I. Hachiya, H. Shibuya, M. Shimizu*
Tetrahedron Letters 2003, 44 (10), 2061-2063. DOI:
35. Novel 2-Pyridone Synthesis via Nucleophilic Addition of Malonic Esters to Alkynyl Imines
I. Hachiya, K. Ogura, M. Shimizu*
Organic Letters 2002, 4 (16), 2755-2757. DOI:
34. Designed Ligands as Probes of the Catalytic Binding Mode in Mo-Catalyzed Asymmetric Allylic Alkylation
M. Trost,* K. Dogra, I. Hachiya, T. Emura, D. L. Hughes, S. Krska, R. A. Reamer, M. Palucki, N. Yasuda, P. J. Reider
Angewante Chemie International Edition 2002, 41 (11), 1929-1932. DOI:
33. Fluoride Ion-Mediated Intramolecular Aldol Cyclization of 7-(t-Butyldimethylsiloxy)-7-octenal
I. Hachiya, N. Kobayashi, H. Kijima, K. Pudhom, T. Mukaiyama*
Chemistry Letters 2000, 29 (8), 932-933. DOI:
32. A Novel Carbocationic Species Paired with Tetrakis(pentafluorophenyl)borate Anion in Catalytic Aldol Reaction
T. Mukaiyama,* M. Yanagisawa, D. Iida, I. Hachiya
Chemistry Letters 2000, 29 (6), 606-607. DOI:
31. An Effective Method for the Preparation of Optically Active Polyoxy 8-Membered Ring Enone Corresponding to B Ring of Taxol
I. Shiina, J. Shibata, Y. Imai, R. Ibuka, H. Fujisawa, I. Hachiya, T. Mukaiyama*
Chemistry Letters 1999, 28 (11), 1145-1146. DOI:
1990~
31. An Effective Method for the Preparation of Optically Active Polyoxy 8-Membered Ring Enone Corresponding to B Ring of Taxol
I. Shiina, J. Shibata, Y. Imai, R. Ibuka, H. Fujisawa, I. Hachiya, T. Mukaiyama*
Chemistry Letters 1999, 28 (11), 1145-1146. DOI:
30. A Route to Z-Endiynes via Pd Catalyzed Alkyne Additions
B. M. Trost,* I. Hachiya, M. C. McIntosh
Tetrahedron Letters 1998, 39 (36), 6445-6448. DOI:
29. Asymmetric Molybdenum-Catalyzed Alkylations
B. M. Trost,* I. Hachiya
Journal of the American Chemical Society 1998, 120 (5), 1104-1105. DOI:
28. The Catalytic Fries Rearrangement and o-Acylation Reactions Using Group 3 and 4 Metal Triflates as Catalysts
S. Kobayashi,* M. Moriwaki, I. Hachiya
Bulletin of the Chemical Society of Japan 1997, 70 (1), 267-273. DOI:
27. Parallel Synthesis Using Mannich-Type Three-Component Reactions and “Field Synthesis” for the Construction of an Amino Alcohol Library
S. Kobayashi,* M. Moriwaki, R. Akiyama, S. Suzuki, I. Hachiya
Tetrahedron Letters 1996, 37 (43), 7783-7786. DOI:
26. Aldol Reactions on Solid Phase. Sc(OTf)3-Catalyzed Aldol Reactions of Polymer-Supported Silyl Enol Ethers with Aldehydes Providing Convenient Methods for the Preparation of 1,3-Diol, β-Hydroxy Carboxylic Acid, and β-Hydroxy Aldehyde Libraries
S. Kobayashi,* I. Hachiya, M. Yasuda
Tetrahedron Letters 1996, 37 (31), 5569-5572. DOI:
25. Catalytic Direct C-Acylation of Phenol and Naphthol Derivatives Using Carboxylic Acids as Acylating Reagents
S. Kobayashi,* M. Moriwaki, I. Hachiya
Tetrahedron Letters 1996, 37 (24), 4183-4186. DOI:
24. Trichlorosilane-Dimethylformamide (Cl3SiH-DMF) as an Efficient Reducing Agent. Reduction of Aldehydes and Imines and Reductive Amination of Aldehydes under Mild Conditions Using Hypervalent Hydridosilicates
S. Kobayashi,* M. Yasuda, I. Hachiya
Chemistry Letters 1996, 25 (5), 407-408. DOI:
23. Polymer-Supported Silyl Enol Ethers. Synthesis and Reactions with Imines for the Preparation of an Amino Alcohol Library
S. Kobayashi,* I. Hachiya, S. Suzuki, M. Moriwaki
Tetrahedron Letters 1996, 37 (16), 2809-2812. DOI:
22. Hafnium Trifluoromethanesulfonate (Hf(OTf)4) as an Efficient Catalyst in the Fries Rearrangement and Direct Acylation of Phenol and Naphthol Derivatives
S. Kobayashi,* M. Moriwaki, I. Hachiya
Tetrahedron Letters 1996, 37 (12), 2053-2056. DOI:
21. 2-Acylation Reactions of Phenol and 1-Naphthol Derivatives Using Sc(OTf)3 as a Lewis Acid Catalyst
S. Kobayashi,* M. Moriwaki, I. Hachiya
Synlett 1995, 6 (11), 1153‑1154. DOI:
20. The Catalytic Fries Rearrangement of Acyloxy Naphthalenes Using Scandium Trifluoromethanesulfonate as a Catalyst
S. Kobayashi,* M. Moriwaki, I. Hachiya
Journal of the Chemical Society, Chemical Communications 1995, (15), 1527-1528. DOI:
19. Hafnium(IV) Trifluoromethanesulfonate, an Efficient Catalyst for the Friedel-Crafts Acylation and Alkylation Reactions
I. Hachiya, M. Moriwaki, S. Kobayashi*
Bulletin of the Chemical Society of Japan 1995, 68 (7), 2053-2060. DOI:
18. Molecular Recognition by Artificial Chiral Catalysts Utilizing a Metal Chelate. A Remarkable Difference in Reactivity Between Geometrical Isomers of Silyl Enolates in Asymmetric Aldol Reactions Using Chiral Tin(II) Catalysts
S. Kobayashi,* M. Horibe I. Hachiya
Tetrahedron Letters 1995, 36 (18), 3173-3176. DOI:
17. Activation of Imines by Rare Earth Metal Triflates. Ln(OTf)3- or Sc(OTf)3-Catalyzed Reactions of Imines with Silyl Enolates and Diels-Alder Reactions of Imines
S. Kobayashi,* M. Araki, H. Ishitani, S. Nagayama, I. Hachiya
Synlett 1995, 6 (3), 233‑234. DOI:
16. Catalytic Friedel-Crafts Acylation Reactions Using Hafnium Triflate as a Catalyst in Lithium Perchlorate-Nitromethane
I. Hachiya, M. Moriwaki, S. Kobayashi*
Tetrahedron Letters 1995, 36 (3), 409-412. DOI:
15. Asymmetric Diels-Alder Reactions Catalyzed by Chiral Lanthanide(III) Trifluoromethanesulfonates. Unique Structure of the Triflate and Stereoselective Synthesis of Both Enantiomers Using a Single Chiral Source and a Choice of Achiral Ligands
S. Kobayashi,* H. Ishitani, I. Hachiya, M. Araki
Tetrahedron 1994, 50 (40), 11623-11636. DOI:
14. Characterization of Chiral Ytterbium and Scandium Catalysts Based on Their Trifluoromethanesulfonates in Asymmetric Diels-Alder Reactions
S. Kobayashi,* H. Ishitani, M. Araki, I. Hachiya
Tetrahedron Letters 1994, 35 (34), 6325-6328. DOI:
13. A Chiral Scandium Catalyst for Enantioselective Diels-Alder Reactions
S. Kobayashi,* M. Araki, I. Hachiya
The Journal of Organic Chemistry 1994, 59 (14), 3758-3759. DOI:
12. Repeated Use of the Catalyst in Ln(OTf)3-Catalyzed Aldol and Allylation Reactions
S. Kobayashi,* I. Hachiya, Y. Yamanoi
Bulletin of the Chemical Society of Japan 1994, 67 (8), 2342-2344. DOI:
11. Lanthanide Triflates as Water-Tolerant Lewis Acids. Activation of Commercial Formaldehyde Solution and Use in the Aldol Reaction of Silyl Enol Ethers with Aldehydes in Aqueous Media
S. Kobayashi,* I. Hachiya
The Journal of Organic Chemistry 1994, 59 (13), 3590-3596. DOI:
10. Scandium(III) Perchlorate (Sc(ClO4)3). A Novel Catalyst in the α-C- and N-Glycosylation Reactions
I. Hachiya, S. Kobayashi*
Tetrahedron Letters 1994, 35 (20), 3319-3320. DOI:
9. Aqueous Reactions with a Lewis Acid and an Organometallic Reagent. The Scandium Trifluoromethanesulfonate-Catalyzed Allylation Reaction of Carbonyl Compounds with Tetraallyltin
I. Hachiya, S. Kobayashi*
The Journal of Organic Chemistry 1993, 58 (25), 6958-6960. DOI:
8. Scandium Trifluoromethanesulfonate (Sc(OTf)3) as a Novel Reusable Lewis Acid Catalyst in Aldol and Michael Reactions
S. Kobayashi,* I. Hachiya, H. Ishitani, M. Araki
Synlett 1993, 4 (7), 472‑474. DOI:
7. Asymmetric Diels-Alder Reaction Catalyzed by a Chiral Ytterbium Trifluoromethanesulfonate
S. Kobayashi,* I. Hachiya, H. Ishitani, M. Araki
Tetrahedron Letters 1993, 34 (28), 4535-4538. DOI:
6. Scandium Trifluoromethanesulfonate (Sc(OTf)3). A Novel Reusable Catalyst in the Diels-Alder Reaction
S. Kobayashi,* I. Hachiya, M. Araki, H. Ishitani
Tetrahedron Letters 1993, 34 (23), 3755-3758. DOI:
5. Lanthanide Trifluoromethanesulfonates as Reusable Catalysts. Aldol Reactions in Organic Solvents
S. Kobayashi,* I. Hachiya, T. Takahori
Synthesis 1993, 25 (4), 371-3734. DOI:
4. Lanthanide Trifluoromethanesulfonates as Reusable Catalysts. Michael and Diels-Alder Reactions
S. Kobayashi,* I. Hachiya, T. Takahori, M. Araki, H. Ishitani
Tetrahedron Letters 1992, 33 (45), 6815-6818. DOI:
3. The Aldol Reaction of Silyl Enol Ethers with Aldehyeds in Aqueous Media
S. Kobayashi,* I. Hachiya
Tetrahedron Letters 1992, 33 (12), 1625-1628. DOI:
2. Stereoselective Synthesis of Both Diastereomers of the α-Methyl-β-hydroxy-β-alkyl(aryl) Units by Use of Tin(II) Triflate-Mediated Aldol Reaction
S. Kobayashi,* I. Hachiya
The Journal of Organic Chemistry 1992, 57 (5), 1324-1326. DOI:
1. An Efficient Asymmetric Aldol Reaction Promoted by a Chiral Tin(II) Lewis Acid Consisting of Tin(II) Triflate, (R)-2-[(N-1-Naphthylamino)methyl]tetrahydrothiophene and a Tin(IV) Compound
T. Mukaiyam,* H. Asanuma, I. Hachiya, T. Harada, S. Kobayashi
Chemistry Letters 1991, 20 (7), 1209-1210. DOI:
MISC
17. 四ヨウ化チタンのヨードチタン化能力を活用する新規合成反応
八谷 巌，溝田 功，清水 真
有機合成化学協会誌 2017, 75 (12), 1226‑1237.
16. Metal Iodides-Mediated Reactions
M. Shimizu, I. Hachiya, J. Inanaga
Iodine: Chemistry and Application; Kaiho, T., Ed; (John Wiley & Sons: Hoboken, NJ) 2015, 329-351.
15. Titanium Tetraiodide Mediated Organic Reactions
T. Kaneishi, I. Hachiya, M. Shimizu
Arabian Journal of Science and Engineering 2014, 39 (9), 6599‑6616.
14. Chemoselective Reductions and Iodinations Using Titanium Tetraiodide
I. Hachiya, M. Shimizu
Tetrahedron Letters 2014, 55 (17), 2781-2788.
13. Synthesis of Nitrogen-Containing Heterocycles Using Conjugate Addition Reactions of Nucleophiles to α,β-Unsaturated Imines
I. Hachiya, I. Mizota, M. Shimizu
Heterocycles 2012, 85, (5), 993-1016.
12. ヨウ化チタンを用いる有機分子変換反応の開発
清水 真，西 隆文，溝田 功，八谷 巌
東海化学工業会会報 2012, 272, 4-9.
11. 第6章 有機化学・第2節 脂肪族炭化水素の化学・コラム
八谷 巌
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10. 第2章 合成・重合法・第1節 EDOTの効率的な合成法
清水 真，八谷 巌
PEDOTの材料物性とデバイス応用; 奥崎秀典 監修（サイエンス＆テクノロジー） 2011, 17-23.
9. 第19章 ヨウ化チタンの反応
清水 真，八谷 巌
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8. α,β-不飽和イミンへの共役付加反応を用いる新規合成反応
八谷 巌，清水 真
有機合成化学協会誌 2010, 68 (10), 1006‑1016.
7. No.46 アルキニルイミンへの共役付加反応, No.71 アルコキシカルボニルイミニウム塩の反応, No.177 α-イミノエステルへのタンデム反応
清水 真，八谷 巌
使える！有機合成反応241実践ガイド; 丸岡啓二、野崎京子、石井康敬、大寺純蔵、富岡 清 編著（化学同人） 2010, 92-93, 142-143, 358-359.
6. Conjugate Imines and Iminium Salts as Versatile Acceptors of Nucleophile
M. Shimizu, I. Hachiya, I. Mizota
Chemical Communications 2009, 45 (8), 874-889.
5. 向山アルドール反応：高選択的炭素－炭素結合生成反応
八谷 巌
化学と教育 2009, 57 (9), 416-417.
4. 活性メチン化合物のアルキニルイミンおよびケトンへの共役付加反応を用いる新規合成反応
八谷 巌，清水 真
有機合成化学協会誌 2006, 64 (3), 251‑262.
3. 2 金属別分類－有機金属化合物を当量用いる有機合成反応－2.14 銅を用いる有機合成反応
清水 真，八谷 巌
第5版実験化学講座18巻 有機化合物の合成VI; 日本化学会編（丸善） 2004, 280-310.
2. Rare Earth Metal Complexes as Water-Tolerant Lewis Acid Catalysts in Organic Synthesis
S. Kobayashi, I. Hachiya, H. Ishitani, M. Moriwaki S. Nagayama
Russian Journal of Organic Chemistry 1996, 32 (2), 191-202.
1. 水溶液中でのルイス酸触媒反応
小林 修，八谷 巌
有機合成化学協会誌 1995, 53 (5), 370‑380.